My guess was also 6 point NFL teasers, on favorites with the line between -7.5 and -8.5. Not sure how many teams, so I'll guess two.

Ding ding ding.

A 6 point 2-team teaser, purchased at the most widely available -110, requires teams to cover the spread +6 points 72.4% of the time to break even. A basic strategy teaser is to take teams across the 3 and 7...that is tease dogs up across the 3 and 7 and favorites down across the 7 and 3. However, a closer look reveals that only the home favorite subset has won more than 72.4% of the time in the last 15 years.

Basic Strategy 2-team, 6 point teaser summary, last 15 years:
RD +1.5 to +2.5.......201-78-0 for 72%, sample size 279
HD +1.5 to +2.5.......146-56-0 for 72.3%, sample size 202
RF -7.5 to -8.5.........43-22-0 for 66.2%, sample size 65
HF -7.5 to -8.5..........167-59-2 for 73.9% sample size 228

Thus, at -110, the player has a 1.5% edge teasing home favorites of -7.5 - 8.5 down six points. If you can find a 6 pt. teaser at even money (there are only a few rogue books left that offer them), then the breakeven point is 70.7. That would give you a 3.2% edge...definitely worth playing.

There are no plays for this subset this week at the current lines.

Ding ding ding.

Any reason why this wouldn't apply to the college game as well? I can think of a few possible reasons, but if you had the numbers in a database to run, it would be interesting to see the results.

Irish Boy, you are so smart.