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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:24 am 
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Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit. Not only was the data it was based on total bullshit, but there was no peer review process prior to publication, and the data and methodology were so bunk that the company behind the data wouldn't even submit to the peer review instituted after enough people called bullshit. But remember, TRUST THE SCIENCE!
This is a good nomination but this is also why you don't rush through unproven treatments for diseases without clear evidence. Pretty much all the evidence for or against it didn't reach the standard you are complaining about not being met here.
There were trials being done to see if the treatment was viable against COVID that his paper halted. Aren't clinical trials a crucial part of gathering evidence on a treatment?
There were plenty of trials that still were going on. They haven't found it to make a difference though.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:25 am 
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Boilermaker Rick wrote:
Jaw Breaker wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit. Not only was the data it was based on total bullshit, but there was no peer review process prior to publication, and the data and methodology were so bunk that the company behind the data wouldn't even submit to the peer review instituted after enough people called bullshit. But remember, TRUST THE SCIENCE!
This is a good nomination but this is also why you don't rush through unproven treatments for diseases without clear evidence. Pretty much all the evidence for or against it didn't reach the standard you are complaining about not being met here.


Off-label use of a drug is very common. As denis said, this medicine has been used for 60 years.

It doesn't matter if the drug has been around a while. They need to make sure that it won't hurt, and then that it will help, before it becomes a standard practice to use it.



It matters a lot. If someone figured out Advil was the cure, don't you think most people would be pretty comfortable fast-tracking it?

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:28 am 
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Jaw Breaker wrote:
It matters a lot. If someone figured out Advil was the cure, don't you think most people would be pretty comfortable fast-tracking it?
It hasn't been found to matter at all though. You saw how the system works. The drug was already approved with little to no evidence that it works and was being used on Americans who were sick.

https://www.reuters.com/article/us-health-coronavirus-hydroxychloroquine/uk-halts-trial-of-hydroxychloroquine-as-useless-for-covid-19-patients-idUSKBN23C1YM

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:28 am 
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Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit. Not only was the data it was based on total bullshit, but there was no peer review process prior to publication, and the data and methodology were so bunk that the company behind the data wouldn't even submit to the peer review instituted after enough people called bullshit. But remember, TRUST THE SCIENCE!
This is a good nomination but this is also why you don't rush through unproven treatments for diseases without clear evidence. Pretty much all the evidence for or against it didn't reach the standard you are complaining about not being met here.
There were trials being done to see if the treatment was viable against COVID that his paper halted. Aren't clinical trials a crucial part of gathering evidence on a treatment?


Well the UK halted in Friday because they found it to be useless. Had nothing to do with The Lancet study.

Quote:
UK halts trial of hydroxychloroquine as 'useless' for COVID-19 patients
Kate Kelland and Alistair Smout


LONDON (Reuters) - British scientists halted a major drug trial on Friday after it found that the anti-malarial hydroxychloroquine, touted by U.S. President Donald Trump as a potential "game changer" in the pandemic, was "useless" at treating COVID-19 patients.

"This is not a treatment for COVID-19. It doesn't work," Martin Landray, an Oxford University professor who is co-leading the RECOVERY trial, told reporters.

"This result should change medical practice worldwide. We can now stop using a drug that is useless."

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:42 am 
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long time guy wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit. Not only was the data it was based on total bullshit, but there was no peer review process prior to publication, and the data and methodology were so bunk that the company behind the data wouldn't even submit to the peer review instituted after enough people called bullshit. But remember, TRUST THE SCIENCE!
This is a good nomination but this is also why you don't rush through unproven treatments for diseases without clear evidence. Pretty much all the evidence for or against it didn't reach the standard you are complaining about not being met here.
There were trials being done to see if the treatment was viable against COVID that his paper halted. Aren't clinical trials a crucial part of gathering evidence on a treatment?


Well the UK halted in Friday because they found it to be useless. Had nothing to do with The Lancet study.

Quote:
UK halts trial of hydroxychloroquine as 'useless' for COVID-19 patients
Kate Kelland and Alistair Smout


LONDON (Reuters) - British scientists halted a major drug trial on Friday after it found that the anti-malarial hydroxychloroquine, touted by U.S. President Donald Trump as a potential "game changer" in the pandemic, was "useless" at treating COVID-19 patients.

"This is not a treatment for COVID-19. It doesn't work," Martin Landray, an Oxford University professor who is co-leading the RECOVERY trial, told reporters.

"This result should change medical practice worldwide. We can now stop using a drug that is useless."
That's interesting. Of what relevance is it here?


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:44 am 
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Juice's Lecture Notes wrote:
long time guy wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit. Not only was the data it was based on total bullshit, but there was no peer review process prior to publication, and the data and methodology were so bunk that the company behind the data wouldn't even submit to the peer review instituted after enough people called bullshit. But remember, TRUST THE SCIENCE!
This is a good nomination but this is also why you don't rush through unproven treatments for diseases without clear evidence. Pretty much all the evidence for or against it didn't reach the standard you are complaining about not being met here.
There were trials being done to see if the treatment was viable against COVID that his paper halted. Aren't clinical trials a crucial part of gathering evidence on a treatment?


Well the UK halted in Friday because they found it to be useless. Had nothing to do with The Lancet study.

Quote:
UK halts trial of hydroxychloroquine as 'useless' for COVID-19 patients
Kate Kelland and Alistair Smout


LONDON (Reuters) - British scientists halted a major drug trial on Friday after it found that the anti-malarial hydroxychloroquine, touted by U.S. President Donald Trump as a potential "game changer" in the pandemic, was "useless" at treating COVID-19 patients.

"This is not a treatment for COVID-19. It doesn't work," Martin Landray, an Oxford University professor who is co-leading the RECOVERY trial, told reporters.

"This result should change medical practice worldwide. We can now stop using a drug that is useless."
That's interesting. Of what relevance is it here?


You're being disingenuous. That's why it's relevant.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:48 am 
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Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:49 am 
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long time guy wrote:
Juice's Lecture Notes wrote:
long time guy wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit. Not only was the data it was based on total bullshit, but there was no peer review process prior to publication, and the data and methodology were so bunk that the company behind the data wouldn't even submit to the peer review instituted after enough people called bullshit. But remember, TRUST THE SCIENCE!
This is a good nomination but this is also why you don't rush through unproven treatments for diseases without clear evidence. Pretty much all the evidence for or against it didn't reach the standard you are complaining about not being met here.
There were trials being done to see if the treatment was viable against COVID that his paper halted. Aren't clinical trials a crucial part of gathering evidence on a treatment?


Well the UK halted in Friday because they found it to be useless. Had nothing to do with The Lancet study.

Quote:
UK halts trial of hydroxychloroquine as 'useless' for COVID-19 patients
Kate Kelland and Alistair Smout


LONDON (Reuters) - British scientists halted a major drug trial on Friday after it found that the anti-malarial hydroxychloroquine, touted by U.S. President Donald Trump as a potential "game changer" in the pandemic, was "useless" at treating COVID-19 patients.

"This is not a treatment for COVID-19. It doesn't work," Martin Landray, an Oxford University professor who is co-leading the RECOVERY trial, told reporters.

"This result should change medical practice worldwide. We can now stop using a drug that is useless."
That's interesting. Of what relevance is it here?


You're being disingenuous. That's why it's relevant.
Disingenuous about what?


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:51 am 
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Antarctica wrote:
Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


Well when you are able to establish that are scientists that are still conducting research on it in the UK then feel free to let the class know. Otherwise the statement stands. Litigation's statement was false.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:53 am 
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Juice's Lecture Notes wrote:
Disingenuous about what?


The paper didn't "halt" anything if there were still scientists conducting research on it.
Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:53 am 
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long time guy wrote:
Antarctica wrote:
Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


Well when you are able to establish that are scientists that are still conducting research on it in the UK then feel free to let the class know. Otherwise the statement stands. Litigation's statement was false.
What statement was false?


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:54 am 
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Juice's Lecture Notes wrote:
long time guy wrote:
Antarctica wrote:
Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


Well when you are able to establish that are scientists that are still conducting research on it in the UK then feel free to let the class know. Otherwise the statement stands. Litigation's statement was false.
What statement was false?


This one.

Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 8:57 am 
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long time guy wrote:
Juice's Lecture Notes wrote:
long time guy wrote:
Antarctica wrote:
Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


Well when you are able to establish that are scientists that are still conducting research on it in the UK then feel free to let the class know. Otherwise the statement stands. Litigation's statement was false.
What statement was false?


This one.

Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit.
There were trials that were halted as a result of the paper. This is a fact. I did not say "halted all trials".

You're pathetically trying to create a "gotcha" here, and it isn't working too well.


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:03 am 
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Juice's Lecture Notes wrote:
long time guy wrote:
Juice's Lecture Notes wrote:
long time guy wrote:
Antarctica wrote:
Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


Well when you are able to establish that are scientists that are still conducting research on it in the UK then feel free to let the class know. Otherwise the statement stands. Litigation's statement was false.
What statement was false?


This one.

Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit.
There were trials that were halted as a result of the paper. This is a fact. I did not say "halted all trials".

You're pathetically trying to create a "gotcha" here, and it isn't working too well.


You initially claimed it "pretty much halted trials" and now that you claim that "there were some trials" that were halted and you don't understand that these are completely different statements

You suck at reading comprehension.

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Last edited by long time guy on Mon Jun 08, 2020 9:04 am, edited 1 time in total.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:04 am 
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long time guy wrote:
Juice's Lecture Notes wrote:
long time guy wrote:
Juice's Lecture Notes wrote:
long time guy wrote:
Antarctica wrote:
Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


Well when you are able to establish that are scientists that are still conducting research on it in the UK then feel free to let the class know. Otherwise the statement stands. Litigation's statement was false.
What statement was false?


This one.

Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit.
There were trials that were halted as a result of the paper. This is a fact. I did not say "halted all trials".

You're pathetically trying to create a "gotcha" here, and it isn't working too well.


You initially claimed it "pretty much halted trials" and now that you claim that "there were some trials" that were halted.

Your original statement was false.

You have to score this a long time guy victory.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:11 am 
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long time guy wrote:
Juice's Lecture Notes wrote:
long time guy wrote:
Juice's Lecture Notes wrote:
long time guy wrote:
Antarctica wrote:
Its also disingenuous to say "the UK" are giving up when its actually more like it seems a few individual British scientists are giving up. That would be like saying if GM went out of business that "America is giving up on carmaking".


Well when you are able to establish that are scientists that are still conducting research on it in the UK then feel free to let the class know. Otherwise the statement stands. Litigation's statement was false.
What statement was false?


This one.

Juice's Lecture Notes wrote:
Turns out the paper that pretty much halted trials of hydroxychloroquine as a treatment for COVID was total bullshit.
There were trials that were halted as a result of the paper. This is a fact. I did not say "halted all trials".

You're pathetically trying to create a "gotcha" here, and it isn't working too well.


You initially claimed it "pretty much halted trials" and now that you claim that "there were some trials" that were halted and you don't understand that these are completely different statements

You suck at reading comprehension.
:lol: Ok, LTG, there was one trial that wasn't halted by The Lancet ignoring the peer review process to publish a bunk study just because it countered Trump.


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:13 am 
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Juice's Lecture Notes wrote:
:lol: Ok, LTG, there was one trial that wasn't halted by The Lancet ignoring the peer review process to publish a bunk study just because it countered Trump.
There it is. It only was a matter of time.

It was researched worldwide and there was no solid evidence that it made a difference. Other trials have ended early because there was no evidence it mattered.

A "cure" for this disease that is proven probably gives the researchers a Nobel Prize and worldwide acclaim in the medical community. I'm sure they all stopped though because it would have made Trump look correct.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:16 am 
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Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
:lol: Ok, LTG, there was one trial that wasn't halted by The Lancet ignoring the peer review process to publish a bunk study just because it countered Trump.
There it is. It only was a matter of time.

It was researched worldwide and there was no solid evidence that it made a difference. Other trials have ended early because there was no evidence it mattered.

A "cure" for this disease that is proven probably gives the researchers a Nobel Prize and worldwide acclaim in the medical community. I'm sure they all stopped though because it would have made Trump look correct.
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:19 am 
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Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:19 am 
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JLN is having a rough thread.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:20 am 
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Juice's Lecture Notes wrote:
:lol: Ok, LTG, there was one trial that wasn't halted by The Lancet ignoring the peer review process to publish a bunk study just because it countered Trump.


There were more than simply "one trial that wasn't halted" Litigation Notes. You seem to have a problem with facts.
Quote:
The anti-inflammatory drug hydroxychloroquine does not significantly reduce admission to intensive care or death in patients hospitalized with pneumonia due to COVID-19, finds a study from France. And a randomized clinical trial from China shows that hospitalized patients with mild to moderate persistent covid-19 who received hydroxychloroquine did not clear the virus more quickly than those receiving standard care.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:23 am 
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Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:25 am 
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Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.
What is your proof this was done to hurt Donald Trump?

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:26 am 
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Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.


You falsely claimed that it brought research to a halt when it clearly did not.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:30 am 
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Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.
What is your proof this was done to hurt Donald Trump?
I'm not going through this again. Read the thread. The tweet from the post under OP was retweeted by the journal's editor, and is a specific defense of the editor's politicking and politicization of the journal.


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:36 am 
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long time guy wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.


You falsely claimed that it brought research to a halt when it clearly did not.
This is false.


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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:45 am 
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Juice's Lecture Notes wrote:
long time guy wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.


You falsely claimed that it brought research to a halt when it clearly did not.
This is false.


No it isn't.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:53 am 
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Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.
What is your proof this was done to hurt Donald Trump?
I'm not going through this again. Read the thread. The tweet from the post under OP was retweeted by the journal's editor, and is a specific defense of the editor's politicking and politicization of the journal.


Nothing in the article suggests that this was politically done to hurt Trump yet you falsely claim that it is. Your only "source" regarding it being political is a tweet from some person on Twitter. Shocking!

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:54 am 
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Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Boilermaker Rick wrote:
Juice's Lecture Notes wrote:
Rick, do you not understand the point of DBing The Lancet here? It's not just because it derailed some clinical trials. In fact that point is so insignificant I now wish I hadn't made reference to it.
You could tell me the point instead of having me guess.
A peer-reviewed medical journal ignored their peer review process so they could publish a study that damaged the messaging of a political opponent. Secondary issue: A peer-reviewed medical journal has become so unabashedly political that it can reasonably be said to have political opponents.
What is your proof this was done to hurt Donald Trump?
I'm not going through this again. Read the thread. The tweet from the post under OP was retweeted by the journal's editor, and is a specific defense of the editor's politicking and politicization of the journal.
Oh, a tweet.

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 Post subject: Re: The Lancet
PostPosted: Mon Jun 08, 2020 9:55 am 
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Boilermaker Rick wrote:
Oh, a tweet.


They're just college kids with no real power!


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